The AIMM (Acipimox in Mitochondrial Myopathy) trial is a clinical trial to determine whether a drug, acipimox, can be used to improve muscle symptoms in patients with mitochondrial myopathy (muscle…

Earlier this week, the Wellcome Centre for Mitochondrial Research (WCMR) at Newcastle University announced its search to appoint a new Director as successor to Professor Sir Doug Turnbull.  This is…

Last month, we were delighted to welcome Dr Bette Phimister, Deputy Editor in Chief at New England Journal of Medicine (NEJM), to the WCMR at Newcastle University. During her visit,…

Idebenone is a drug used in the treatment of Leber’s hereditary optic neuropathy (LHON), a mitochondrial disorder that causes vision loss. LHON usually starts with blurred vision in one or…

At the last Young Scientist meeting, PhD students Gareth Ettridge and Polly Usher tackled the topic of drug screening and drug discovery. The session was based around explaining how new…

Last month, first year PhD student Elizaveta Olkhova talked to us about her research project that involves dissecting the molecular mechanisms underpinning hyperexcitable neuronal networks in mitochondrial disease. But what…

Last week, first year PhD student Alex Bury talked to us about his exciting project that uses nanobiopsy to extract mitochondria from live cells. But what exactly does this mean?…

About Prosper 2B (Prospective Observational Study in Patients with Mitochondrial Depletion Syndrome, RRM2B) The Prosper 2B study is a research study funded by The Lily Foundation and Mito Foundation and…

As part of the MRC Science Festival 2019, 15 researchers from the Centre for Ageing and Vitality and Wellcome Centre for Mitochondrial Research at Newcastle University spent an afternoon engaging…

A national cohort study has provided a better understanding of mitochondrial disease caused by mutations in a mitochondrial gene.  This will lead to more rapid diagnosis, improved clinical care and…